Functional specificity of two hormone response elements present on the human apoA-II promoter that bind retinoid X receptor alpha/thyroid receptor beta heterodimers for retinoids and thyroids: synergistic interactions between thyroid receptor beta and upstream stimulatory factor 2a.

DNA binding and mutagenesis in vitro established that the -67/-55 region of the apoA-II (apolipoprotein A-II) promoter contains a thyroid HRE (hormone response element), which strongly binds RXRalpha (retinoid X receptor alpha)/T(3)Rbeta (thyroid receptor beta) heterodimers and weakly T(3)Rbeta homo...

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Hlavní autoři: Hatzivassiliou, Eudoxia, Koukos, George, Ribeiro, Agnes, Zannis, Vassilis, Kardassis, Dimitris
Médium: Artigo
Jazyk:Inglês
Vydáno: 2003
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223787/
https://ncbi.nlm.nih.gov/pubmed/12959642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030549
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