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Role of the glutamate dehydrogenase reaction in furnishing aspartate nitrogen for urea synthesis: studies in perfused rat liver with 15N.

The present study was designed to determine: (i) the role of the reductive amination of alpha-ketoglutarate via the glutamate dehydrogenase reaction in furnishing mitochondrial glutamate and its transamination into aspartate; (ii) the relative incorporation of perfusate 15NH4Cl, [2-15N]glutamine or...

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Main Authors: Nissim, Itzhak, Horyn, Oksana, Luhovyy, Bohdan, Lazarow, Adam, Daikhin, Yevgeny, Nissim, Ilana, Yudkoff, Marc
Formato: Artigo
Idioma:Inglês
Publicado: 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223758/
https://ncbi.nlm.nih.gov/pubmed/12935293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030997
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