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Bcl-2 activates a programme of premature senescence in human carcinoma cells.
The apoptosis regulator Bcl-2 has been shown to modulate cell-cycle progression, favouring a quiescent state over a proliferative state, in both normal and tumour cells. We show here that constitutive expression of Bcl-2 in human carcinoma cells results in a cell-cycle arrest that within a few days...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223693/ https://ncbi.nlm.nih.gov/pubmed/12871207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030868 |
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