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Glucocorticoids suppress beta-cell development and induce hepatic metaplasia in embryonic pancreas.

Elevated glucocorticoids are associated with low birth weight and fetal 'programming' of hypertension and glucose intolerance. In the present paper, we show that treatment of fetal rats with dexamethasone during the last week of gestation reduces the insulin content of their pancreatic bet...

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Detalhes bibliográficos
Main Authors: Shen, Chia-Ning, Seckl, Jonathan R, Slack, Jonathan M W, Tosh, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223676/
https://ncbi.nlm.nih.gov/pubmed/14509268
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