Glucocorticoids suppress beta-cell development and induce hepatic metaplasia in embryonic pancreas.

Elevated glucocorticoids are associated with low birth weight and fetal 'programming' of hypertension and glucose intolerance. In the present paper, we show that treatment of fetal rats with dexamethasone during the last week of gestation reduces the insulin content of their pancreatic bet...

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Detaylı Bibliyografya
Asıl Yazarlar: Shen, Chia-Ning, Seckl, Jonathan R, Slack, Jonathan M W, Tosh, David
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2003
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223676/
https://ncbi.nlm.nih.gov/pubmed/14509268
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