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Glucocorticoids suppress beta-cell development and induce hepatic metaplasia in embryonic pancreas.

Elevated glucocorticoids are associated with low birth weight and fetal 'programming' of hypertension and glucose intolerance. In the present paper, we show that treatment of fetal rats with dexamethasone during the last week of gestation reduces the insulin content of their pancreatic bet...

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Hlavní autoři: Shen, Chia-Ning, Seckl, Jonathan R, Slack, Jonathan M W, Tosh, David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223676/
https://ncbi.nlm.nih.gov/pubmed/14509268
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