Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model

Although implantation of fetal dopamine (DA) neurons can reduce parkinsonism in patients, current methods are rudimentary, and a reliable donor cell source is lacking. We show that transplanting low doses of undifferentiated mouse embryonic stem (ES) cells into the rat striatum results in a prolifer...

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Detalhes bibliográficos
Main Authors: Björklund, Lars M., Sánchez-Pernaute, Rosario, Chung, Sangmi, Andersson, Therese, Chen, Iris Yin Ching, McNaught, Kevin St. P., Brownell, Anna-Liisa, Jenkins, Bruce G., Wahlestedt, Claes, Kim, Kwang-Soo, Isacson, Ole
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122367/
https://ncbi.nlm.nih.gov/pubmed/11782534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022438099
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