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Characterization of non-covalent oligomers of proteins treated with hypochlorous acid.

Hypochlorous acid (HOCl) is a potent oxidant produced by myeloperoxidase that causes aggregation of many proteins. Treatment of apohaemoglobin and apomyoglobin with HOCl produced a regular series of oligomer bands when the proteins were separated by SDS/PAGE under reducing conditions. Aggregation wa...

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Détails bibliographiques
Auteurs principaux: Chapman, Anna L P, Winterbourn, Christine C, Brennan, Stephen O, Jordan, T William, Kettle, Anthony J
Format: Artigo
Langue:Inglês
Publié: 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223668/
https://ncbi.nlm.nih.gov/pubmed/12852783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030685
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