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Heterogeneity of hypochlorous acid production in individual neutrophil phagosomes revealed by a rhodamine-based probe

The rhodamine-based probe R19-S has been shown to react with hypochlorous acid (HOCl) to yield fluorescent R19, but not with some other oxidants including hydrogen peroxide. Here, we further examined the specificity of R19-S and used it for real-time monitoring of HOCl production in neutrophil phago...

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Foilsithe in:J Biol Chem
Main Authors: Albrett, Amelia M., Ashby, Louisa V., Dickerhof, Nina, Kettle, Anthony J., Winterbourn, Christine C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177602/
https://ncbi.nlm.nih.gov/pubmed/30135208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004789
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