Heteromultimers of DEG/ENaC subunits form H(+)-gated channels in mouse sensory neurons

Acidic extracellular solution activates transient H(+)-gated currents in dorsal root ganglion (DRG) neurons. The biophysical properties of three degenerin/epithelial sodium (DEG/ENaC) channel subunits (BNC1, ASIC, and DRASIC), and their expression in DRG, suggest that they might underlie these H(+)-...

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Autors principals: Benson, Christopher J., Xie, Jinghui, Wemmie, John A., Price, Margaret P., Henss, Jillian M., Welsh, Michael J., Snyder, Peter M.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2002
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC122366/
https://ncbi.nlm.nih.gov/pubmed/11854527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032678399
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