Different modes of internalization of apoptotic alkyl-lysophospholipid and cell-rescuing lysophosphatidylcholine.

The synthetic alkyl-lysophospholipid (ALP), Et-18-OCH3 (1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine), can induce apoptosis in tumour cells. Unlike conventional chemotherapeutic drugs, ALP acts at the cell-membrane level. We have reported previously that ALP is internalized, and interferes...

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Detalhes bibliográficos
Main Authors: Van Der Luit, Arnold H, Budde, Marianne, Verheij, Marcel, Van Blitterswijk, Wim J
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223649/
https://ncbi.nlm.nih.gov/pubmed/12837133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030179
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