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Different modes of internalization of apoptotic alkyl-lysophospholipid and cell-rescuing lysophosphatidylcholine.
The synthetic alkyl-lysophospholipid (ALP), Et-18-OCH3 (1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine), can induce apoptosis in tumour cells. Unlike conventional chemotherapeutic drugs, ALP acts at the cell-membrane level. We have reported previously that ALP is internalized, and interferes...
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Hoofdauteurs: | , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2003
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223649/ https://ncbi.nlm.nih.gov/pubmed/12837133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030179 |
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