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Insulin-induced Drosophila S6 kinase activation requires phosphoinositide 3-kinase and protein kinase B.
An important mechanism by which insulin regulates cell growth and protein synthesis is through activation of the p70 ribosomal S6 protein kinase (S6K). In mammalian cells, insulin-induced PI3K (phosphoinositide 3-kinase) activation, generates the lipid second messenger PtdIns(3,4,5) P (3), which is...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2003
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223624/ https://ncbi.nlm.nih.gov/pubmed/12841848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030577 |
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