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The role of two novel regulatory sites in the activation of the cGMP-dependent protein kinase from Plasmodium falciparum.
The Plasmodium falciparum cGMP-dependent protein kinase (PfPKG) uniquely contains three cGMP binding sites, but also has a 'degenerate' fourth site. The role of each cGMP-binding site in PfPKG activation remains unknown. We have analysed the effect of mutation of each cGMP-binding site (in...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2003
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223622/ https://ncbi.nlm.nih.gov/pubmed/12817987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030474 |
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