The role of two novel regulatory sites in the activation of the cGMP-dependent protein kinase from Plasmodium falciparum.

The Plasmodium falciparum cGMP-dependent protein kinase (PfPKG) uniquely contains three cGMP binding sites, but also has a 'degenerate' fourth site. The role of each cGMP-binding site in PfPKG activation remains unknown. We have analysed the effect of mutation of each cGMP-binding site (in...

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Hlavní autoři: Deng, Wensheng, Parbhu-Patel, Asha, Meyer, David J, Baker, David A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2003
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223622/
https://ncbi.nlm.nih.gov/pubmed/12817987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030474
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