S3 to S3' subsite specificity of recombinant human cathepsin K and development of selective internally quenched fluorescent substrates.

We have systematically examined the S3 to S3' subsite substrate specificity requirements of cathepsin K using internally quenched fluorescent peptides derived from the lead sequence Abz-KLRFSKQ-EDDnp [where Abz is o -aminobenzoic acid and EDDnp is N -(2,4-dinitrophenyl)ethylenediamine]. We assa...

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Main Authors: Alves, Marcio F M, Puzer, Luciano, Cotrin, Simone S, Juliano, Maria Aparecida, Juliano, Luiz, Brömme, Dieter, Carmona, Adriana K
Formato: Artigo
Idioma:Inglês
Publicado: 2003
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223542/
https://ncbi.nlm.nih.gov/pubmed/12733990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030438
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