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Cathepsin B carboxydipeptidase specificity analysis using internally quenched fluorescent peptides.

We have examined in detail the specificity of the subsites S1, S2, S1' and S2' for the carboxydipeptidase activity of cathepsin B by synthesizing and assaying four series of internally quenched fluorescent peptides based on the sequence Dnp-GFRFW-OH, where Dnp (2,4-dinitrophenyl) is the qu...

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Detalhes bibliográficos
Main Authors: Cezari, Maria Helena S, Puzer, Luciano, Juliano, Maria Aparecida, Carmona, Adriana K, Juliano, Luiz
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222986/
https://ncbi.nlm.nih.gov/pubmed/12201820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020840
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