Activation of C-terminal Src kinase (Csk) by phosphorylation at serine-364 depends on the Csk-Src homology 3 domain.

In the present study, we investigate the mechanism for the protein kinase A (PKA)-mediated activation of C-terminal Src kinase (Csk). Although isolated Csk kinase domain was phosphorylated at Ser(364) by PKA to the same stoichiometry as wild-type Csk, significant activation of the isolated Csk kinas...

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Detalhes bibliográficos
Main Authors: Yaqub, Sheraz, Abrahamsen, Hilde, Zimmerman, Bastian, Kholod, Natalya, Torgersen, Knut Martin, Mustelin, Tomas, Herberg, Friedrich W, Taskén, Kjetil, Vang, Torkel
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223381/
https://ncbi.nlm.nih.gov/pubmed/12600271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030021
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