U2 small nuclear ribonucleoprotein particle (snRNP) auxiliary factor of 65 kDa, U2AF65, can promote U1 snRNP recruitment to 5' splice sites.

The splicing factor U2AF(65), U2 small nuclear ribonucleoprotein particle (snRNP) auxillary factor of 65 kDa, binds to pyrimidine-rich sequences at 3' splice sites to recruit U2 snRNP to pre-mRNAs. We report that U2AF(65) can also promote the recruitment of U1 snRNP to weak 5' splice sites...

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Hauptverfasser: Förch, Patrik, Merendino, Livia, Martínez, Concepción, Valcárcel, Juan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2003
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223361/
https://ncbi.nlm.nih.gov/pubmed/12558503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021202
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