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Interfacial kinetic analysis of the tumour suppressor phosphatase, PTEN: evidence for activation by anionic phospholipids.

We investigated the kinetic behaviour and substrate specificity of PTEN (phosphatase and tensin homologue deleted on chromosome 10) using unilamellar vesicles containing substrate lipids in a background of phosphatidylcholine. PTEN displays the characteristics expected of an interfacial enzyme, sinc...

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Detalhes bibliográficos
Main Authors: McConnachie, George, Pass, Ian, Walker, Steven M, Downes, C Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223325/
https://ncbi.nlm.nih.gov/pubmed/12534371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021848
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