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Human mismatch-repair protein MutL homologue 1 (MLH1) interacts with Escherichia coli MutL and MutS in vivo and in vitro: a simple genetic system to assay MLH1 function.

A simple genetic system has been developed to test the effect of over-expression of wild-type or mutated human MutL homologue 1 (hMLH1) proteins on methyl-directed mismatch repair (MMR) in Escherichia coli. The system relies on detection of Lac(+) revertants using MMR-proficient or MMR-deficient E....

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Bibliografski detalji
Glavni autori: Quaresima, Barbara, Alifano, Pietro, Tassone, Pierfrancesco, Avvedimento, Enrico V, Costanzo, Francesco S, Venuta, Salvatore
Format: Artigo
Jezik:Inglês
Izdano: 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223262/
https://ncbi.nlm.nih.gov/pubmed/12513688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021205
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