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Thermodynamic characterization of yeast triosephosphate isomerase refolding: insights into the interplay between function and stability as reasons for the oligomeric nature of the enzyme.

The reasons underlying the oligomeric nature of some proteins such as triosephosphate isomerase (TIM) are unclear. It has been proposed that this enzyme is an oligomer, mainly because of its stability rather than for functional reasons. To address this issue, the reversible denaturation and renatura...

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Detalhes bibliográficos
Main Authors: Nájera, Hugo, Costas, Miguel, Fernández-Velasco, D Alejandro
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223230/
https://ncbi.nlm.nih.gov/pubmed/12472469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021439
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