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A novel splice variant of mouse interleukin-1-receptor-associated kinase-1 (IRAK-1) activates nuclear factor-kappaB (NF-kappaB) and c-Jun N-terminal kinase (JNK).

Interleukin-1 (IL-1)-receptor-associated kinase (IRAK) is an indispensable signalling molecule for host-defence responses initiated by a variety of ligands that bind to members of the Toll/IL-1 receptor family. Here we report a novel splice variant of mouse IRAK-1, IRAK-1-S, which is generated by ut...

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Bibliografiske detaljer
Main Authors: Yanagisawa, Ken, Tago, Kenji, Hayakawa, Morisada, Ohki, Motomichi, Iwahana, Hiroyuki, Tominaga, Shin-Ichi
Format: Artigo
Sprog:Inglês
Udgivet: 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223149/
https://ncbi.nlm.nih.gov/pubmed/12418963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021218
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