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Ellman's-reagent-mediated regeneration of trypanothione in situ: substrate-economical microplate and time-dependent inhibition assays for trypanothione reductase.

Trypanothione reductase (TryR) is a key enzyme involved in the oxidative stress management of the Trypanosoma and Leishmania parasites, which helps to maintain an intracellular reducing environment by reduction of the small-molecular-mass disulphide trypanothione (T[S](2)) to its di-thiol derivative...

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Detalhes bibliográficos
Main Authors: Hamilton, Chris J, Saravanamuthu, Ahilan, Eggleston, Ian M, Fairlamb, Alan H
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223126/
https://ncbi.nlm.nih.gov/pubmed/12416994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021298
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