Peroxisome proliferator-activated receptor alpha (PPARalpha)-mediated regulation of multidrug resistance 2 (Mdr2) expression and function in mice.

Peroxisome proliferator-activated receptor alpha (PPARalpha) is a nuclear receptor that controls expression of genes involved in lipid metabolism and is activated by fatty acids and hypolipidaemic fibrates. Fibrates induce the hepatic expression of murine multidrug resistance 2 ( Mdr2 ), encoding th...

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Detalhes bibliográficos
Main Authors: Kok, Tineke, Bloks, Vincent W, Wolters, Henk, Havinga, Rick, Jansen, Peter L M, Staels, Bart, Kuipers, Folkert
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223107/
https://ncbi.nlm.nih.gov/pubmed/12381268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020981
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