Peroxisome-proliferator-activated receptor-alpha (PPARalpha) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin.

The aim of the present study was to determine whether peroxisome-proliferator-activated receptor-alpha (PPARalpha) deficiency disrupts the normal regulation of triacylglycerol (TAG) accumulation, hepatic lipogenesis and glycogenesis by fatty acids and insulin using PPARalpha-null mice. In wild-type...

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Detalhes bibliográficos
Main Authors: Sugden, Mary C, Bulmer, Karen, Gibbons, Geoffrey F, Knight, Brian L, Holness, Mark J
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222580/
https://ncbi.nlm.nih.gov/pubmed/12023878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20011699
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