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The effect of peroxisome-proliferator-activated receptor-alpha on the activity of the cholesterol 7 alpha-hydroxylase gene.

Cholesterol 7 alpha-hydroxylase (Cyp7a1) plays a central role in the regulation of bile acid and cholesterol metabolism, and transcription of the gene is controlled by bile acids and hormones acting through a complex interaction with a number of potential steroid-hormone-binding sites. Transcription...

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Bibliografiska uppgifter
Huvudupphovsmän: Patel, D D, Knight, B L, Soutar, A K, Gibbons, G F, Wade, D P
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2000
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221415/
https://ncbi.nlm.nih.gov/pubmed/11042130
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