A functional activating protein 1 (AP-1) site regulates matrix metalloproteinase 2 (MMP-2) transcription by cardiac cells through interactions with JunB-Fra1 and JunB-FosB heterodimers.

Enhanced synthesis of a specific matrix metalloproteinase, MMP-2, has been demonstrated in experimental models of ventricular failure and in cardiac extracts from patients with ischaemic cardiomyopathy. Cultured neonatal rat cardiac fibroblasts and myocytes were used to analyse the determinants of M...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Bergman, Marina R, Cheng, Sunfa, Honbo, Norman, Piacentini, Lucia, Karliner, Joel S, Lovett, David H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2003
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223099/
https://ncbi.nlm.nih.gov/pubmed/12371906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020707
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge