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Arsenite-induced Cdc25C degradation is through the KEN-box and ubiquitin–proteasome pathway

Arsenite is a known human carcinogen that induces tumorigenesis through either a genotoxic or an epigenetic mechanism. In this study, the effect of arsenite on cell cycle regulation and the mechanisms that contribute to this effect were investigated. Treatment of the cells with arsenite suppressed c...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Chen, Fei, Zhang, Zhuo, Bower, Jacquelyn, Lu, Yongju, Leonard, Stephen S., Ding, Min, Castranova, Vince, Piwnica-Worms, Helen, Shi, Xianglin
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122307/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11842186/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.032428899
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