Dual role for mitogen-activated protein kinase (Erk) in insulin-dependent regulation of Fra-1 (fos-related antigen-1) transcription and phosphorylation.

Insulin regulates the activity of the AP-1 (activator protein-1) transcriptional complex in several cell types. One component of the AP-1 complex is the transcription factor Fra-1 (fos-related antigen-1), and we have demonstrated previously that insulin stimulates the expression of Fra-1 mRNA in CHO...

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Detalhes bibliográficos
Main Authors: Hurd, Toby W, Culbert, Ainsley A, Webster, Kenneth J, Tavaré, Jeremy M
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223008/
https://ncbi.nlm.nih.gov/pubmed/12197835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020579
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