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Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase.

The DNA-dependent protein kinase (DNA-PK) is required for the repair of DNA double-strand breaks (DSBs), such as those caused by ionizing radiation and other DNA-damaging agents. DNA-PK is composed of a large catalytic subunit (DNA-PKcs) and a heterodimer of Ku70 and Ku80 that assemble on the ends o...

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Detalhes bibliográficos
Main Authors: Douglas, Pauline, Sapkota, Gopal P, Morrice, Nick, Yu, Yaping, Goodarzi, Aaron A, Merkle, Dennis, Meek, Katheryn, Alessi, Dario R, Lees-Miller, Susan P
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222982/
https://ncbi.nlm.nih.gov/pubmed/12186630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020973
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