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The DNA-Dependent Protein Kinase Catalytic Subunit Is Phosphorylated In Vivo on Threonine 3950, a Highly Conserved Amino Acid in the Protein Kinase Domain

The protein kinase activity of the DNA-dependent protein kinase (DNA-PK) is required for the repair of DNA double-strand breaks (DSBs) via the process of nonhomologous end joining (NHEJ). However, to date, the only target shown to be functionally relevant for the enzymatic role of DNA-PK in NHEJ is...

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Bibliografische gegevens
Hoofdauteurs: Douglas, Pauline, Cui, Xiaoping, Block, Wesley D., Yu, Yaping, Gupta, Shikha, Ding, Qi, Ye, Ruiqiong, Morrice, Nick, Lees-Miller, Susan P., Meek, Katheryn
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820444/
https://ncbi.nlm.nih.gov/pubmed/17158925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01962-06
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