Human DINB1-encoded DNA polymerase κ is a promiscuous extender of mispaired primer termini

Both in yeast and humans, DNA polymerase (Pol) η functions in the error-free replication of UV-damaged DNA, and Polη has the unique ability to efficiently replicate through a cis-syn thymine–thymine (T–T) dimer by inserting two As opposite the two Ts of the dimer. Although human DINB1-encoded Polκ b...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Washington, M. Todd, Johnson, Robert E., Prakash, Louise, Prakash, Satya
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2002
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122293/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11842189/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.032594399
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!