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Human DINB1-encoded DNA polymerase κ is a promiscuous extender of mispaired primer termini

Both in yeast and humans, DNA polymerase (Pol) η functions in the error-free replication of UV-damaged DNA, and Polη has the unique ability to efficiently replicate through a cis-syn thymine–thymine (T–T) dimer by inserting two As opposite the two Ts of the dimer. Although human DINB1-encoded Polκ b...

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Autori principali: Washington, M. Todd, Johnson, Robert E., Prakash, Louise, Prakash, Satya
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC122293/
https://ncbi.nlm.nih.gov/pubmed/11842189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032594399
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