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Forced engagement of a RNA/protein complex by a chemical inducer of dimerization to modulate gene expression
A general strategy is described for forcing the engagement of an RNA/protein complex by using small-molecule ligands. A bivalent molecule was created by linking a protein-binding ligand to an RNA-binding ligand. On presentation of the chemical inducer of dimerization to the RNA by the protein, coope...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122288/ https://ncbi.nlm.nih.gov/pubmed/11854489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042693399 |
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