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RNA-tethering assay and eIF4G:eIF4A obligate dimer design uncovers multiple eIF4F functional complexes
Eukaryotic cellular mRNAs possess a 5′ cap structure (m(7)GpppN) which plays a critical role in translation initiation mediated by eukaryotic initiation factor (eIF) 4F. The heterotrimeric eIF4F complex possesses several activities imparted by its subunits that include cap recognition (by eIF4E), RN...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7470955/ https://ncbi.nlm.nih.gov/pubmed/32749456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa646 |
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