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Measurement of free and membrane-bound cathepsin G in human neutrophils using new sensitive fluorogenic substrates.

Activated human polymorphonuclear neutrophils at inflammatory sites release the chymotrypsin-like protease cathepsin G, together with elastase and proteinase 3 (myeloblastin), from their azurophil granules. The low activity of cathepsin G on synthetic substrates seriously impairs studies designed to...

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Detalhes bibliográficos
Main Authors: Attucci, Sylvie, Korkmaz, Brice, Juliano, Luiz, Hazouard, Eric, Girardin, Catherine, Brillard-Bourdet, Michèle, Réhault, Sophie, Anthonioz, Philippe, Gauthier, Francis
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222843/
https://ncbi.nlm.nih.gov/pubmed/12088507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020321
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