Catalytic Activity and Inhibition of Wegener Antigen Proteinase 3 on the Cell Surface of Human Polymorphonuclear Neutrophils

Proteinase 3 (Pr3), the main target of anti-neutrophil cytoplasmic antibodies, is a neutrophil serine protease that may be constitutively expressed at the surface of quiescent circulating neutrophils. This raises the question of the simultaneous presence in the circulation of constitutive membrane-b...

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Autors principals: Korkmaz, Brice, Jaillet, Jérôme, Jourdan, Marie-Lise, Gauthier, Alexandre, Gauthier, Francis, Attucci, Sylvie
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Enzyme Catalysis and Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740415/
https://ncbi.nlm.nih.gov/pubmed/19447886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M901471200
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