A mammalian Rho-specific guanine-nucleotide exchange factor (p164-RhoGEF) without a pleckstrin homology domain.

Rho GTPases, which are activated by specific guanine-nucleotide exchange factors (GEFs), play pivotal roles in several cellular functions. We identified a recently cloned human cDNA, namely KIAA0337, encoding a protein containing 1510 amino acids (p164). It contains a RhoGEF-specific Dbl homology (D...

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Autori principali: Rümenapp, Ulrich, Freichel-Blomquist, Andrea, Wittinghofer, Burkhard, Jakobs, Karl H, Wieland, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2002
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222833/
https://ncbi.nlm.nih.gov/pubmed/12071859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020654
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