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Use of double-stranded RNA-mediated interference to determine the substrates of protein tyrosine kinases and phosphatases.

Despite the wealth of information generated by genome-sequencing projects, the identification of in vivo substrates of specific protein kinases and phosphatases is hampered by the large number of candidate enzymes, overlapping enzyme specificity and sequence similarity. In the present study, we demo...

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Main Authors: Muda, Marco, Worby, Carolyn A, Simonson-Leff, Nancy, Clemens, James C, Dixon, Jack E
Format: Artigo
Jezik:Inglês
Izdano: 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222762/
https://ncbi.nlm.nih.gov/pubmed/12014990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020298
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