Tumour necrosis factor-induced activation of c-Jun N-terminal kinase is sensitive to caspase-dependent modulation while activation of mitogen-activated protein kinase (MAPK) or p38 MAPK is not.

The activation of the extracellular signal-regulated kinases (ERKs) by tumour necrosis factor-alpha (TNF) receptors (TNFRs) is an integral part of the cytokine's pleiotropic cellular responses. Here we report differences in the caspase sensitivity and TNFR subtype activation of members of the E...

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Detalhes bibliográficos
Main Authors: Mohamed, Ahmed A A, Jupp, Orla J, Anderson, Helen M, Littlejohn, Alison F, Vandenabeele, Peter, MacEwan, David J
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222751/
https://ncbi.nlm.nih.gov/pubmed/11996667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020527
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