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Role of caspases in dexamethasone-induced apoptosis and activation of c-Jun NH(2)-terminal kinase and p38 mitogen-activated protein kinase in human eosinophils

Eosinophils are the principal effector cells for the pathogenesis of allergic inflammation. Glucocorticoids such as dexamethasone have long been used therapeutically for eosinophilia in allergic inflammation by inducing eosinophil apoptosis, but little is known about the intracellular mechanisms med...

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Bibliografiske detaljer
Main Authors: Zhang, J P, Wong, C K, Lam, C W K
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905760/
https://ncbi.nlm.nih.gov/pubmed/11012613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01344.x
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