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Activation of p38 Mitogen-Activated Protein Kinase and c-Jun NH(2)-Terminal Kinase by Double-Stranded RNA and Encephalomyocarditis Virus: Involvement of RNase L, Protein Kinase R, and Alternative Pathways
Double-stranded RNA (dsRNA) accumulates in virus-infected mammalian cells and signals the activation of host defense pathways of the interferon system. We describe here a novel form of dsRNA-triggered signaling that leads to the stimulation of the p38 mitogen-activated protein kinase (p38 MAPK) and...
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Główni autorzy: | , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
American Society for Microbiology
2000
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC85147/ https://ncbi.nlm.nih.gov/pubmed/10611240 |
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