Activation of p38 Mitogen-Activated Protein Kinase and c-Jun NH(2)-Terminal Kinase by Double-Stranded RNA and Encephalomyocarditis Virus: Involvement of RNase L, Protein Kinase R, and Alternative Pathways

Double-stranded RNA (dsRNA) accumulates in virus-infected mammalian cells and signals the activation of host defense pathways of the interferon system. We describe here a novel form of dsRNA-triggered signaling that leads to the stimulation of the p38 mitogen-activated protein kinase (p38 MAPK) and...

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Bibliografiska uppgifter
Huvudupphovsmän: Iordanov, Mihail S., Paranjape, Jayashree M., Zhou, Aimin, Wong, John, Williams, Bryan R. G., Meurs, Eliane F., Silverman, Robert H., Magun, Bruce E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2000
Ämnen:
Cell Growth and Development
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC85147/
https://ncbi.nlm.nih.gov/pubmed/10611240
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