Identification of protein-derived tyrosyl radical in the reaction of cytochrome c and hydrogen peroxide: characterization by ESR spin-trapping, HPLC and MS.

The reaction of cytochrome c and H(2)O(2) is known to form a protein-centred radical that can be detected with the spin trap 2-methyl-2-nitrosopropane (MNP). To characterize the MNP/tyrosyl adduct structure that had previously been determined incorrectly [Barr, Gunther, Deterding, Tomer and Mason (1...

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Detalhes bibliográficos
Main Authors: Qian, Steven Yue, Chen, Yeong-Renn, Deterding, Leesa J, Fann, Yang C, Chignell, Colin F, Tomer, Kenneth B, Mason, Ronald P
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222476/
https://ncbi.nlm.nih.gov/pubmed/11931655
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