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Complementary whole-genome technologies reveal the cellular response to proteasome inhibition by PS-341

Although the biochemical targets of most drugs are known, the biological consequences of their actions are typically less well understood. In this study, we have used two whole-genome technologies in Saccharomyces cerevisiae to determine the cellular impact of the proteasome inhibitor PS-341. By com...

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Detalhes bibliográficos
Main Authors: Fleming, James A., Lightcap, Eric S., Sadis, Seth, Thoroddsen, Vala, Bulawa, Christine E., Blackman, Ronald K.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122213/
https://ncbi.nlm.nih.gov/pubmed/11830665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032516399
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