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Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes
Phosphorylation of proteins on serine/threonine residues preceding proline is a key signaling mechanism. The conformation and function of a subset of these phosphorylated proteins is regulated by the prolyl isomerase Pin1 through isomerization of phosphorylated Ser/Thr-Pro bonds. Although young Pin1...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122191/ https://ncbi.nlm.nih.gov/pubmed/11805292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032404099 |
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