Llwytho...

Protein topology and stability define the space of allowed sequences

We describe a new approach to explore and quantify the sequence space associated with a given protein structure. A set of sequences are optimized for a given target structure, using all-atom models and a physical energy function. Specificity of the sequence for its target is ensured by using the ran...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Koehl, Patrice, Levitt, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The National Academy of Sciences 2002
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC122181/
https://ncbi.nlm.nih.gov/pubmed/11805293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032405199
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