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The thioesterase domain from a nonribosomal peptide synthetase as a cyclization catalyst for integrin binding peptides

Nonribosomal peptide synthetases responsible for the production of macrocyclic compounds often use their C-terminal thioesterase (TE) domain for enzymatic cyclization of a linear precursor. The excised TE domain from the nonribosomal peptide synthetase responsible for the production of the cyclic de...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Kohli, Rahul M., Takagi, Junichi, Walsh, Christopher T.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2002
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122175/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11805307/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.251668398
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