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The thioesterase domain from a nonribosomal peptide synthetase as a cyclization catalyst for integrin binding peptides

Nonribosomal peptide synthetases responsible for the production of macrocyclic compounds often use their C-terminal thioesterase (TE) domain for enzymatic cyclization of a linear precursor. The excised TE domain from the nonribosomal peptide synthetase responsible for the production of the cyclic de...

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Bibliographic Details
Main Authors: Kohli, Rahul M., Takagi, Junichi, Walsh, Christopher T.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC122175/
https://ncbi.nlm.nih.gov/pubmed/11805307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.251668398
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