PchC Thioesterase Optimizes Nonribosomal Biosynthesis of the Peptide Siderophore Pyochelin in Pseudomonas aeruginosa

In Pseudomonas aeruginosa, the antibiotic dihydroaeruginoate (Dha) and the siderophore pyochelin are produced from salicylate and cysteine by a thiotemplate mechanism involving the peptide synthetases PchE and PchF. A thioesterase encoded by the pchC gene was found to be necessary for maximal produc...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Reimmann, Cornelia, Patel, Hiten M., Walsh, Christopher T., Haas, Dieter
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2004
Assuntos:	Physiology and Metabolism
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC516611/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15375116/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.186.19.6367-6373.2004
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